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柴胡皂苷A

分析標準品,HPLC≥98%

Saikosaponin A

CAS號：20736-09-8

分子式：C42H68O13

分子量：780.98

別名：柴胡皂甙A; 柴胡皂苷 A;;SAILKOSAPONIN A; SaikosaponinA; SAILKOSAPONINS A; Saikosaponian A; Saikosaponin a std.

產品介紹

熔點：225-235℃

沸點：893.7℃ at 760 mmHg

比旋光度：(EtOH)+46

外觀：白色粉末

儲存條件：2-8℃

注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻(52篇)

52. [IF=5.4] Lihua Cui et al."Hu Gan Tang ameliorates metabolic-associated fatty liver disease by inhibiting ferroptosis through the Nrf2/GPX4 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2025 Sep;353:120342

51. [IF=4.4] Zheng Liang et al."The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis."MEDIATORS OF INFLAMMATION.2024 Oct;2024(1):4777789

50. [IF=2.9] Menglin Wang et al."Saikosaponin A alleviates depressive-like behavior induced by reserpine in mice by regulating gut microflora and inflammatory responses."PLoS One.2025 Feb;20(2):e0311207

49. [IF=4] Dongbo Li et al."Integrated metabolomics and intestinal microbiota analysis to reveal anti-post-weaning diarrhea mechanisms of Modified Yupingfeng Granule in Rex rabbits."Frontiers in Microbiology.2025 Apr;16:

48. [IF=4.3] Zhang Wenli et al."Evaluation of different ecological regions for cultivation of best quality Bupleurum: a case study from Shanxi, China."BMC PLANT BIOLOGY.2025 Dec;25(1):1-14

47. [IF=4.4] Yingchao Wu et al."Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway."Frontiers in Pharmacology.2025 Apr;16:

46. [IF=4.8] Wei Li et al."Kaempferol modulates ɑ2M secretion in bone marrow-derived macrophages by downregulating GR/PER1-mediated lipid metabolism to attenuate the emotional stress-aggravated metastasis of prostate cancer."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jan;339:1

45. [IF=4.1] Shengwei Zhou et al."Suitable concentrations of brassinolide application enhances growth performance and saikosaponin biosynthesis by transcriptional activation of triterpenoid pathway genes in Bupleurum chinense DC."Frontiers in Plant Science.2025 Mar;16

44. [IF=4.4] Nan Li et al."Wuling capsule alleviates hyperuricaemia and protects UA- injured HK-2 cells by regulating uric acid transporter proteins."Frontiers in Pharmacology.2025 Apr;16:

43. [IF=5.4] Ruolan Sun et al."Homotherapy-for-heteropathy of Bupleurum Chinense DC.-Scutellaria baicalensis Georgi in treating depression and colorectal cancer: A network pharmacology and animal model approach."JOURNAL OF ETHNOPHARMACOLOGY".2024 Mar;:118038

42. [IF=3.4] Jiaxin Yin et al."Comprehensive multicomponent characterization and quality assessment of Xiaoyao Wan by UPLC-Q-Orbitrap-MS, HS-SPME-GC-MS and HS-GC-IMS."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2024 Feb;239:115910

41. [IF=4.1] Liangliang He et al."A multi-module structure labelled molecular network orients the chemical profiles of traditional Chinese medicine prescriptions: Xiaoyao San, as an example."JOURNAL OF CHROMATOGRAPHY A.2024 Jan;1715:464613

40. [IF=5.4] Liangxin Zhao et al."UPLC-Q-Exactive/MS based analysis explore the correlation between components variations and anti-influenza virus effect of four quantified extracts of Chaihu Guizhi decoction."JOURNAL OF ETHNOPHARMACOLOGY.2023 Oct;:117318

39. [IF=2.6] Liu Xueqi et al."In Vivo Evaluation of Self-assembled nano-Saikosaponin-a for Epilepsy Treatment."MOLECULAR BIOTECHNOLOGY.2023 Aug;:1-11

38. [IF=4.6] Zhenhuan Wang et al."Quantitative and Differential Analysis between Bupleurum chinense DC. and Bupleurum scorzonerifolium Willd. Using HPLC-MS and GC-MS Coupled with Multivariate Statistical Analysis."MOLECULES.2023 Jan;28(15):5630

37. [IF=3.1] Tian Lan et al."Saikosaponin A triggers cell ferroptosis in hepatocellular carcinoma by inducing endoplasmic reticulum stress-stimulated ATF3 expression."BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.2023 Sep;674:10

36. [IF=5.4] Jie Tang et al."Study on the mechanism of Shuganzhi Tablet against nonalcoholic fatty liver disease and lipid regulation effects of its main substances in vitro."JOURNAL OF ETHNOPHARMACOLOGY.2023 Nov;316:116780

35. [IF=4.141] Yiqing Peng et al."Assessment of Genetic Diversity in Bupleurum spp. Basing Agronomic Traits, Medicinal Components and ISSR Markers."Genes.2023 Apr;14(4):951

34. [IF=6.656] Minna Huang et al."Saikosaponin A and D attenuate skeletal muscle atrophy in chronic kidney disease by reducing oxidative stress through activation of PI3K/AKT/Nrf2 pathway."PHYTOMEDICINE.2023 Jun;114:154766

33. [IF=3.369] Li Liu et al."Effects of Trichoderma harzianum biofertilizer on growth, yield, and quality of Bupleurum chinense."Plant Direct.2022 Nov;6(11):e461

32. [IF=9.756] Jiling Feng et al."Saikosaponin A enhances Docetaxel efficacy by selectively inducing death of dormant prostate cancer cells through excessive autophagy."CANCER LETTERS.2023 Feb;554:216011

31. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

30. [IF=4.927] Linlin Yang et al."Drought Stress Stimulates the Terpenoid Backbone and Triterpenoid Biosynthesis Pathway to Promote the Synthesis of Saikosaponin in Bupleurum chinense DC. Roots."MOLECULES.2022 Jan;27(17):5470

29. [IF=2.977] An-rong Wang et al."Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway."Behav Brain Res. 2021 Apr;403:113138

28. [IF=3] Qu  Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

27. [IF=3.205] Jie Tang et al."Metabolite profiling of Shuganzhi tablets in rats and pharmacokinetics study of four bioactive compounds with liquid chromatography combined with electrospray ionization tandem mass spectrometry."J Chromatogr B. 2021 Aug;1179:122827

26. [IF=4.36] Xiaojing Zhang et al."A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway."J Ethnopharmacol. 2022 Jan;283:114742

25. [IF=4.534] Jikun  Du et al."Saikosaponin-A induces apoptosis of cervical cancer through mitochondria- and endoplasmic reticulum stress-dependent pathway in vitro and in vivo: involvement of PI3K/AKT signaling pathway."Cell Cycle. 2021;20(21):2221-2232

24. [IF=5.81] Cui  Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway."Front Pharmacol. 2021 Jun;0:1369

23. [IF=3.205] Zhuangzhuang Li et al."Simultaneous quantification of fifteen compounds in rat plasma by LC-MS/MS and its application to a pharmacokinetic study of Chaihu-Guizhi decoction."J Chromatogr B. 2019 Jan;1105:15

22. [IF=3.216] Yu Hong et al."Saikosaponin A modulates remodeling of Kv4.2-mediated A-type voltage-gated potassium currents in rat chronic temporal lobe epilepsy."Drug Des Dev Ther. 2018; 12: 2945–2958

21. [IF=4.411] Dan-Dan Tian et al."Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats."Molecules. 2016 Jun;21(6):696

20. [IF=4.411] Wei Wang et al."In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism."Molecules. 2016 May;21(5):597

19.  Wang, Wei, Dan-Dan Tian, and Zhang-Jin Zhang. "In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism." Molecules 21.5 (2016): 597.https:##doi.org/10.3390/molecules21050597

18.  Tian D-D, Wang W, Wang H-N, Sze SCW, Zhang Z-J. Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats. Molecules. 2016; 21(6):696. https:##doi.org/10.3390/molecules

17.  李壯壯, 張靜, 趙紹哲,等. 指紋圖譜與化學計量學結合優選柴胡桂枝顆粒水提工藝[J]. 中成藥, 2018, v.40(08):199-203.

16.  黃湘  陳豐連  曹騁 等. HPLC-ELSD全成分指紋圖譜研究疏肝理脾方配伍前后化學成分的變化[J]. 化學與生物工程  2020  037(001):59-64.

15.  楊夢玲, 尤朋濤, 何麗珊,等. 基于UPLC-MS/MS分析胃潰瘍模型大鼠口服加味小柴胡顆粒后血漿中8種有效成分的藥代動力學[J]. 中國中藥雜志, 2018, 43(18).

14.  趙昕彤, 辛國, 辛宇,等. 煎煮時間對柴胡中柴胡皂苷A和柴胡皂苷D含量的影響[J]. 人參研究, 2017.

13.  廖念, 龐雪, 周逸群,等. 正交試驗法優選北柴胡麩炒工藝[J]. 中國藥師, 2017, 020(004):738-740.

12.  潘龍,牛俊麗,卜登攀,杜洪,程建波,孫先枝,王秀敏,秦俊杰,袁耀明,張幸開.柴胡皂苷對體外發酵參數及細菌數量變化的影響[J].草業學報,2015,24(06):85-91.

11.  朱雙龍,陳旭義,段會全,劉迎節,孫中磊,徐云強.柴胡皂苷a影響大鼠急性脊髓損傷后機體炎癥水平表達的實驗研究[J].天津醫科大學學報,2017,23(04):300-303.

10.  朱雙龍, 段會全, 劉英富,等. 柴胡皂苷a對大鼠急性脊髓損傷的神經保護作用與機制研究[J]. 中國修復重建外科雜志, 2017, 031(007):825-829.

9.  胡冬蓉, 禤正正, 謝煒,等. 柴胡疏肝湯高效液相指紋圖譜的建立及含量測定[J]. 時珍國醫國藥, 2017(6):1310-1314.

8.  曹雪, 蔡廣知, 趙凌,等. 基于復合質量常數的北柴胡飲片等級評價[J]. 中國實驗方劑學雜志, 2018(18).

7.  李英, 焦倩, 張天天,等. 基于地形因子的河北省北柴胡生態適宜性區劃研究[J]. 中國中藥雜志, 2017, 042(022):4402-4407.

6.  郭泰麟  李丹丹  張慧. 南北柴胡HPLC-ELSD指紋圖譜的研究[J]. 中國民族民間醫藥  2020  029(006):19-24.

5.  廖念  龐雪  周逸群 等. 北柴胡麩煨工藝的正交試驗法優選[J]. 時珍國醫國藥  2017(05):96-98.

4.  龐雪  廖念  周逸群 等. 不同炮制方法對北柴胡中柴胡皂苷含量的影響[J]. 時珍國醫國藥  2016(12):2906-2908.

3.  邱云  蘇健  龐雪 等. 不同炮制方法對北柴胡中柴胡皂苷a、d的含量影響[J]. 湖南中醫藥大學學報  2016(2期):51-53.

2.  寧艷梅 楊秀娟 陳暉 張金保 楊韜 任遠.不同比例鱉血炮制柴胡制品中柴胡總皂苷含量測定與比較[J].中獸醫醫藥雜志 2019 38(05):9-13.

1.  辛國  趙昕彤  李文 等. 不同時間煎煮柴胡對五柴胡飲中柴胡皂苷含量及藥效學的影響[J]. 長春中醫藥大學學報  2018(4):641-644.

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